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Description for Protein NID2

nidogen 2 (osteonidogen)
9 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/0)
(platelet: 3; secretome: 1)
Summary:
This gene encodes a member of the nidogen family of basement membrane proteins. This protein is a cell-adhesion protein that binds collagens I and IV and laminin and may be involved in maintaining the structure of the basement membrane. (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • NIDO: Extracellular domain of unknown function in nidogen (entactin) and hypothetical proteins.
  • G2F: G2 nidogen domain and fibulin
  • EGFCA: Calcium-binding EGF-like domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K06826
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Osteonidogen
    Approved Symbol:
    NID2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 05654 Entrez Gene ID: 22795 OMIM ID: 605399 Swissprot Accession: Q14112;