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Description for Protein FIGF

c-fos induced growth factor (vascular endothelial growth factor D)
4 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family and is active in angiogenesis, lymphangiogenesis, and endothelial cell growth. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-2 and VEGFR-3 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor C. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • PDGF: Platelet-derived and vascular endothelial growth factors (PDGF, VEGF) family
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K05449
    KEGG - Pathway(s):
    hsa04060; hsa04150; hsa04510; hsa05200; hsa05211; hsa05212; hsa05219
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Vascular endothelial growth factor D; VEGF-D; c-fos induced growth factor; FOS-induced growth factor
    Approved Symbol:
    FIGF
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02102 Entrez Gene ID: 2277 OMIM ID: 300091 Swissprot Accession: O43915;