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Description for Protein FER

fer (fps/fes related) tyrosine kinase
16 total interacting proteins; 12 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(platelet: 2; undefined: 1)
Summary:
Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • FCH: Fes/CIP4 homology domain
  • CC: Coiled Coil
  • SH2: Src homology 2 domains
  • Tyr_Kinase: tyrosine kinase domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.10.2
    KEGG - Orthology:
    K08889
    KEGG - Pathway(s):
    hsa04520
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    FPS/FES related tyrosine kinase; Protein tyrosine kinase 3; TYK3; Proto oncogene tyrosine protein kinase FER; p94-FER; c-FER
    Approved Symbol:
    FER
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 10
    Human (de-) phosphorylation sites: 10; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 6
    Human phosphorylation targets: 6; Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01491 Entrez Gene ID: 2241 OMIM ID: 176942 Swissprot Accession: P16591; Q05DA5;