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Description for Protein ALDH9A1

aldehyde dehydrogenase 9 family, member A1
5 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 1)
Summary:
This protein belongs to the aldehyde dehydrogenase family of proteins. It has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    1.2.1.19; 1.2.1.3; 1.2.1.47
    KEGG - Orthology:
    K00128
    K00137
    K00149
    KEGG - Pathway(s):
    hsa00010; hsa00053; hsa00071; hsa00280; hsa00310; hsa00330; hsa00340; hsa00380; hsa00410; hsa00561; hsa00620; hsa00640; hsa00650; hsa00903; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    ALDH9; Gamma aminobutyraldehyde dehydrogenase; R-aminobutyraldehyde dehydrogenase; E3
    Approved Symbol:
    ALDH9A1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 6
    Human (de-) phosphorylation sites: 6; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • NADH(db);
  • Nicotinamide-Adenine-Dinucleotide(db)

    Associated Genetic Diseases:

  • ALDH9A1*2 polymorphism(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04109 Entrez Gene ID: 223 OMIM ID: 602733 Swissprot Accession: P49189; B9EKV4;