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Description for Protein FCN2

ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)
2 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The product of this gene belongs to the ficolin family of proteins. This family is characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. This gene is predominantly expressed in the liver, and has been shown to have carbohydrate binding and opsonic activities. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • FBG: Fibrinogen-related domains (FReDs)
  • COLL: Collagen triple helix repeat (20 copies)
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K10104
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    EBP37; Hucolin; L-Ficolin; Ficolin B; Collagen/fibrinogen domain-containing protein 2; Serum lectin p35; Ficolin 2 isoform b precursor; Ficolin 2 isoform a precursor
    Approved Symbol:
    FCN2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 1
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 03376 Entrez Gene ID: 2220 OMIM ID: 601624 Swissprot Accession: Q15485;