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Description for Protein FCGR3B

Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
2 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
(PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • IG: Immunoglobulin
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K06463
    KEGG - Pathway(s):
    hsa04650; hsa05140; hsa05322
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Fc fragment of IgG, low affinity IIIb, receptor for (CD16); Low affinity immunoglobulin gamma Fc region receptor III-B; IgG Fc receptor III-1; Fc-gamma RIII-beta; FcR3B; FcR3; CD16-B; FcR-10; CD16; FCG3; FCGR3
    Approved Symbol:
    FCGR3B
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Abciximab(db);
  • Adalimumab(db);
  • Alefacept(db);
  • Alemtuzumab(db);
  • Basiliximab(db);
  • Bevacizumab(db);
  • Cetuximab(db);
  • Daclizumab(db);
  • Efalizumab(db);
  • Etanercept(db);
  • Gemtuzumab ozogamicin(db);
  • Ibritumomab(db);
  • Intravenous Immunoglobulin(db);
  • Muromonab(db);
  • Natalizumab(db);
  • Palivizumab(db);
  • Rituximab(db);
  • Tositumomab(db);
  • Trastuzumab(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 09951 Entrez Gene ID: 2215 OMIM ID: 610665 Swissprot Accession: O75015;