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Description for Protein FCER2

Fc fragment of IgE, low affinity II, receptor for (CD23)
4 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(undefined: 1)
Summary:
The human leukocyte differentiation antigen CD23 (FCE2) is a key molecule for B-cell activation and growth. It is the low-affinity receptor for IgE. The truncated molecule can be secreted, then functioning as a potent mitogenic growth factor.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • LECTIN_C: C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K06468
    KEGG - Pathway(s):
    hsa04640
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    IgE binding factor; IGEBF; Immunoglobulin E receptor low affinity II; IgE receptor lymphocyte; Low affinity immunoglobin epsilon FC receptor; lymphocyte IgE recceptor; FC epsilon RII; BLAST 2; Immunoglobulin E binding factor
    Approved Symbol:
    FCER2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 01049 Entrez Gene ID: 2208 OMIM ID: 151445 Swissprot Accession: P06734;