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Description for Protein FARSA

phenylalanyl-tRNA synthetase, alpha subunit
5 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/1)
(platelet: 1; undefined: 1)
Summary:
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. This gene encodes a product which is similar to the catalytic subunit of prokaryotic and Saccharomyces cerevisiae phenylalanyl-tRNA synthetases (PheRS). This gene product has been shown to be expressed in a tumor-selective and cell cycle stage- and differentiation-dependent manner, the first member of the tRNA synthetase gene family shown to exhibit this type of regulated expression [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
6.1.1.20
KEGG - Orthology:
K01889
KEGG - Pathway(s):
hsa00970
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
PheRS; Phenylalanine-tRNA ligase alpha chain; CML33; Phenylalanine-tRNA synthetase-like
Approved Symbol:
FARSA
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 3
Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • L-Phenylalanine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04227 Entrez Gene ID: 2193 OMIM ID: 602918 Swissprot Accession: Q6IBR2; Q9Y285;