Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein ACSL1

acyl-CoA synthetase long-chain family member 1
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 2/0)
(membrane: 1; platelet: 10)
Summary:
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    6.2.1.3
    KEGG - Orthology:
    K01897
    KEGG - Pathway(s):
    hsa00071; hsa01100; hsa03320; hsa04146; hsa04920
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Long chain acyl CoA synthetase 2; LACS2; Palmitoyl CoA ligase 2; LACS; Long chain fatty acid coenzyme A ligase 2; Long-chain fatty acid coenzyme A ligase 1; LACS1; Palmitoyl-CoA ligase; Lignoceroyl CoA synthase; ACS1; FACL1; FACL2; Fatty acid CoA ligase long chain 1
    Approved Symbol:
    ACSL1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 3
    Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Adenosine monophosphate(db);
  • Adenosine triphosphate(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 01068 Entrez Gene ID: 2180 OMIM ID: 152425 Swissprot Accession: P33121;