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Description for Protein ETS2

v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
22 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • ETS: erythroblast transformation specific domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K02678
    KEGG - Pathway(s):
    hsa04320
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    V ETS avian erythroblastosis virus E26 oncogene homolog 2; Oncogene ETS2; ETS2 oncogene
    Approved Symbol:
    ETS2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 5
    Human (de-) phosphorylation sites: 5; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01263 Entrez Gene ID: 2114 OMIM ID: 164740 Swissprot Accession: P15036;