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Description for Protein ESD

esterase D
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 5/1)
(microparticles: 1; platelet: 4; secretome: 1)
Summary:
This gene encodes a serine hydrolase that belongs to the esterase D family. The encoded enzyme is active toward numerous substrates including O-acetylated sialic acids, and it may be involved in the recycling of sialic acids. This gene is used as a genetic marker for retinoblastoma and Wilson's disease. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
3.1.2.12
KEGG - Orthology:
K01070
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
FGH; S-formylglutathionehydrolase; OTTHUMP00000040929; EC 3.1.1.1
Approved Symbol:
ESD
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 2
Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Glutathione(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00588 Entrez Gene ID: 2098 OMIM ID: 133280 Swissprot Accession: P10768;