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Description for Protein ERF

Ets2 repressor factor
5 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Members of the ETS family of transcription factors, such as ERF, regulate cell proliferation and differentiation. They share a highly conserved DNA-binding domain, the ETS domain, that recognizes the sequence GGAA/T (de Castro et al., 1997 [PubMed 9192842]). For further information on ETS transcription factors, see ETS1 (MIM 164720).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • ETS: erythroblast transformation specific domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K09434
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    ETS-domain transcription factor ERF; Ets2 repressor factor; PE-2
    Approved Symbol:
    ERF
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 27
    Human (de-) phosphorylation sites: 27; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09942 Entrez Gene ID: 2077 OMIM ID: 611888 Swissprot Accession: P50548;