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Description for Protein HIPK1

homeodomain interacting protein kinase 1
9 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene belongs to the Ser/Thr family of protein kinases and HIPK subfamily. It phosphorylates homeodomain transcription factors and may also function as a co-repressor for homeodomain transcription factors. Alternative splicing results in four transcript variants encoding four distinct isoforms. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • S_T_kinase: Serine/Threonine protein kinases, catalytic domain

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    2.7.11.1
    KEGG - Orthology:
    K08826
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Nuclear body associated kinase 2b; Homeodomain interacting protein kinase 1; Homeodomain interacting protein kinase 1-like protein; Myak; Nbak2; KIAA0630; MGC26642; MGC33446; MGC33548; Homeodomain-interacting protein kinase 1 isoform 3; Homeodomain interacting protein kinase 1 isoform 2; Homeodomain interacting protein kinase 1 isoform 4; Homeodomain-interacting protein kinase 1 isoform 1
    Approved Symbol:
    HIPK1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 28
    Human (de-) phosphorylation sites: 28; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 06418 Entrez Gene ID: 204851 OMIM ID: 608003 Swissprot Accession: Q86Z02