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Description for Protein EPB41L1

erythrocyte membrane protein band 4.1-like 1
13 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
Erythrocyte membrane protein band 4.1 (EPB41) is a multifunctional protein that mediates interactions between the erythrocyte cytoskeleton and the overlying plasma membrane. The protein encoded by this gene is a neuronally-enriched protein that is structurally similar to EPB41. The encoded protein binds and stabilizes D2 and D3 dopamine receptors at the neuronal plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them has been determined. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • B41: Band 4.1 homologues
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K06107
    KEGG - Pathway(s):
    hsa04530
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Nonerythroid protein 4.1 neuron type; Neuronal protein 4.1; 4.1N; KIAA0338; MGC11072; Neuron type nonerythroid protein 4.1; Erythrocyte membrane protein band 4.1 like 1 isoform b; Erythrocyte membrane protein band 4.1 like 1 isoform a
    Approved Symbol:
    EPB41L1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 65
    Human (de-) phosphorylation sites: 65; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04193 Entrez Gene ID: 2036 OMIM ID: 602879 Swissprot Accession: Q9H4G0;