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Description for Protein TUBB

tubulin, beta
51 total interacting proteins; 21 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 11/1)
(alpha granules: 1; cAMP/cGMP binding: 1; membrane: 3; microparticles: 1; platelet: 7; secretome: 1)
Summary:
(PubMed Links)
Domains and Motifs:
  • TUBULIN: Tubulin/FtsZ family, GTPase domain
  • CC: Coiled Coil
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K07375
    KEGG - Pathway(s):
    hsa04540; hsa05130
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    TUBB1; TUBB5; MGC16435; MGC117247; Tubulin, beta polypeptide; Beta Ib tubulin; Tubulin beta-1 chain; Tubulin beta-5 chain; Beta 5-tubulin; M40
    Approved Symbol:
    TUBB
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 21
    Human (de-) phosphorylation sites: 21; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Colchicine(db);
  • Epothilone B(db);
  • Epothilone D(db);
  • Podofilox(db);
  • Vinblastine(db);
  • Vincristine(db);
  • Vinorelbine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 01852 Entrez Gene ID: 203068 OMIM ID: 191130 Swissprot Accession: P07437; Q5SU16;