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Description for Protein ENO2

enolase 2 (gamma, neuronal)
17 total interacting proteins; 7 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 7/2)
(microparticles: 1; platelet: 6; secretome: 1; undefined: 1)
Summary:
This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
4.2.1.11
KEGG - Orthology:
K01689
KEGG - Pathway(s):
hsa00010; hsa01100; hsa03018
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Enolase, gamma; Enolase, neuron specific; NSE; 2 phospho D glycerate hydrolyase; Neural enolase; Gamma enolase; Enolase 2, gamma, neuronal; Neurone specific enolase; Neuron specific gamma enolase; EC 4.2.1.11
Approved Symbol:
ENO2
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 7
Human (de-) phosphorylation sites: 7; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • 2-Phosphoglycolic Acid(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00573 Entrez Gene ID: 2026 OMIM ID: 131360 Swissprot Accession: P09104; Q6FHV6;