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Description for Protein SPRED2

sprouty-related, EVH1 domain containing 2
4 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
SPRED2 is a member of the Sprouty (see SPRY1; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1; MIM 176948) (Nonami et al., 2004 [PubMed 15465815]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • WH1: WASP homology region 1
  • SPRY: Domain in SPla and the RYanodine Receptor.
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K04703
    KEGG - Pathway(s):
    hsa04630
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    FLJ21897; FLJ31917; Sprouty protein with EVH1 domain 2 related sequence
    Approved Symbol:
    SPRED2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 10
    Human (de-) phosphorylation sites: 10; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 18100 Entrez Gene ID: 200734 OMIM ID: 609292 Swissprot Accession: Q7Z698; B3KPL5;