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Description for Protein APLF

aprataxin and PNKP like factor
7 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks (Iles et al., 2007 [PubMed 17353262]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • FHA: Forkhead associated domain

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    4.2.99.18
    KEGG - Orthology:
    K13295
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Chromosome 2 open reading frame 13; MGC47799; C2orf13 protein; Xip1; PNK and APTX-like FHA protein; APFL
    Approved Symbol:
    APLF
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 1
    Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 09848 Entrez Gene ID: 200558 OMIM ID: 611035 Swissprot Accession: Q8IW19