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Description for Protein EIF2C3

eukaryotic translation initiation factor 2C, 3
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K11593
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
AGO3; RP4-789D17.2; FLJ12765; MGC86946; Argonaute 3; Eukaryotic translation initiation factor 2C, 3 isoform a; Eukaryotic translation initiation factor 2C, 3 isoform b
Approved Symbol:
EIF2C3
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 8
Human (de-) phosphorylation sites: 8; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09558 Entrez Gene ID: 192669 OMIM ID: 607355 Swissprot Accession: Q9H9G7; B1ALI0;