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Description for Protein DOCK2

dedicator of cytokinesis 2
7 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(undefined: 1)
Summary:
The DOCK2 gene encodes a hematopoietic cell-specific CDM family protein that is indispensable for lymphocyte chemotaxis.[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • SH3: Src homology 3 domains
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K12367
    KEGG - Pathway(s):
    hsa04062; hsa04666
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    KIAA0209; Dedicator of cyto-kinesis 2
    Approved Symbol:
    DOCK2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 16
    Human (de-) phosphorylation sites: 16; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09121 Entrez Gene ID: 1794 OMIM ID: 603122 Swissprot Accession: Q5XG91; Q92608;