Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein TRDMT1

tRNA aspartic acid methyltransferase 1
9 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
2.1.1.37
KEGG - Orthology:
K00558
KEGG - Pathway(s):
hsa00270; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
PuMet; M.HsaIIP; OTTHUMP00000045198; DNA MTase homolog HsaIIP; DNA (cytosine-5-)-methyltransferase 2; DNA methyltransferase homolog HsaIIP; DNA methyltransferase 2 isoform c; DNA methyltransferase 2 isoform b; DNA methyltransferase 2 isoform a
Approved Symbol:
TRDMT1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Beta-Mercaptoethanol(db);
  • Cysteine Sulfenic Acid(db);
  • Glycerol(db);
  • Pentamidine(db);
  • S-Adenosyl-L-Homocysteine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 6 : 0
  • Isoform 5 : 0
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 16001 Entrez Gene ID: 1787 OMIM ID: 602478 Swissprot Accession: O14717; Q6ICS7;