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Description for Protein DHX9

DEAH (Asp-Glu-Ala-His) box polypeptide 9
37 total interacting proteins; 14 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
This gene encodes a member of the DEAH-containing family of RNA helicases. The encoded protein is an enzyme that catalyzes the ATP-dependent unwinding of double-stranded RNA and DNA-RNA complexes. This protein localizes to both the nucleus and the cytoplasm and functions as a transcriptional regulator. This protein may also be involved in the expression and nuclear export of retroviral RNAs. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 11 and 13. (PubMed Links)
Domains and Motifs:
  • DSRM: Double-stranded RNA binding motif
  • DEXDc: DEAD-like helicases superfamily
  • HELIC: helicase superfamily c-terminal domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.6.1.-
    KEGG - Orthology:
    K13184
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    DDX9; LKP; NDH II; NDHII; RHA; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 9 RNA helicase A; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 9 (RNA helicase A); DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 9 RNA helicase A, nuclear DNA helicase II; Leukophysin; DEAD/H box-9 (nuclear DNA helicase II; RNA helicase A); Nuclear DNA helicase II; DEAH-box protein 9; DEAH (Asp-Glu-Ala-His) box polypeptide 9 isoform 1
    Approved Symbol:
    DHX9
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 32
    Human (de-) phosphorylation sites: 32; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04386 Entrez Gene ID: 1660 OMIM ID: 603115 Swissprot Accession: Q08211; Q58F26;