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Description for Protein DDX6

DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
4 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 1)
Summary:
This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • DEXDc: DEAD-like helicases superfamily
  • HELIC: helicase superfamily c-terminal domain

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    3.6.1.-
    KEGG - Orthology:
    K12614
    KEGG - Pathway(s):
    hsa03018
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Dead/H Box 6; RNA Helicase, 54 KD; p54; Helicase, RNA, Nuclear 2; HLR2
    Approved Symbol:
    DDX6
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 7
    Human (de-) phosphorylation sites: 7; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • D-tartaric acid(db)


    Associated Genetic Diseases:

    None Available
  • Predicted Transmembrane Domains:
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 02638 Entrez Gene ID: 1656 OMIM ID: 600326 Swissprot Accession: P26196