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Description for Protein DCI

dodecenoyl-CoA isomerase
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 2/0)
(platelet: 1; secretome: 2)
Summary:
This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available

Gene Ontology:
Gene Ontology Annotations

KEGG - Enzyme ID(s):
5.3.3.8
KEGG - Orthology:
K13238
KEGG - Pathway(s):
hsa00071
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Dodecenoyl Coenzyme A delta isomerase; 3,2 trans enoyl Coenzyme A isomerase; 3,2-trans-enoyl-CoA isomerase,mitochondrial
Approved Symbol:
DCI
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites

Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • Benzamidine(db);
  • Octanoyl-Coenzyme A(db)


    Associated Genetic Diseases:

    None Available
  • Predicted Transmembrane Domains:
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 02628 Entrez Gene ID: 1632 OMIM ID: 600305 Swissprot Accession: P42126