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Description for Protein AP2B1

adaptor-related protein complex 2, beta 1 subunit
37 total interacting proteins; 21 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 3/0)
(membrane: 1; microparticles: 1; platelet: 1)
Summary:
The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K11825
KEGG - Pathway(s):
hsa04144; hsa05016
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
CLAPB1; Clathrin adaptor complex AP2 beta; ADTB2; DKFZp781K0743; AP105B; Plasma membrane adaptor HA2/AP2 adaptin beta subunit; AP2-Beta; Adaptin, beta 2 (beta); Clathrin assembly protein complex 2 beta large chain; Clathrin-associated/assembly/adaptor protein, large, beta 1; Adaptor-related protein complex 2, beta 1 subunit isoform a; Adaptor-related protein complex 2, beta 1 subunit isoform b
Approved Symbol:
AP2B1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 15
Human (de-) phosphorylation sites: 15; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03015 Entrez Gene ID: 163 OMIM ID: 601025 Swissprot Accession: P63010; Q96EL6;