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Description for Protein ADRB3

adrenergic, beta-3-, receptor
4 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K04143
    KEGG - Pathway(s):
    hsa04020; hsa04080; hsa04144; hsa04970
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    -
    Approved Symbol:
    ADRB3
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Arbutamine(db);
  • Bopindolol(db);
  • Bupranolol(db);
  • Clenbuterol(db);
  • Droxidopa(db);
  • Ephedra(db);
  • Fenoterol(db);
  • Isoproterenol(db);
  • Norepinephrine(db);
  • Propranolol(db)

    Associated Genetic Diseases:

  • Obesity, susceptibility to(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 7
    • Additional Identifiers:

    HPRD: 00188 Entrez Gene ID: 155 OMIM ID: 109691 Swissprot Accession: P13945; A8KAG8;