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Description for Protein CUX1

cut-like homeobox 1
22 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(membrane: 1)
Summary:
The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • HOX: Homeodomain
  • CC: Coiled Coil
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K09313
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    CCAAT displacement protein isoform b; CCAAT displacement protein isoform c; CCAAT displacement protein isoform a; CCAAT displacement protein; CDP; Cut homeobox; Cux; p75; CASP; COY1; p100; p110; p200
    Approved Symbol:
    CUX1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 30
    Human (de-) phosphorylation sites: 30; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 1
  • Isoform 2 : 1
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00295 Entrez Gene ID: 1523 OMIM ID: 116896 Swissprot Accession: Q13948; P39880;