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Description for Protein CTPS

CTP synthase
4 total interacting proteins; 3 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/1)
(phosphoproteome: 1; platelet: 2; undefined: 1)
Summary:
The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
6.3.4.2
KEGG - Orthology:
K01937
KEGG - Pathway(s):
hsa00240; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
CTP synthetase; CTP synthase; UTP ammonia ligase; EC 6.3.4.2
Approved Symbol:
CTPS
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 18
Human (de-) phosphorylation sites: 18; Platelet phosphorylation sites: 5
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

  • L-Glutamine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00465 Entrez Gene ID: 1503 OMIM ID: 123860 Swissprot Accession: P17812;