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Description for Protein CSNK2B

casein kinase 2, beta polypeptide
68 total interacting proteins; 33 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/1)
(platelet: 29; undefined: 1)
Summary:
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K03115
KEGG - Pathway(s):
hsa04310; hsa04520; hsa04530
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
G5a; EC 2.7.1.37; EC 2.7.11.1; Casein kinase 2, beta polypeptide; CSKN2B; Casein kinase II, beta subunit; CK2B; Phosvitin; CKII beta
Approved Symbol:
CSNK2B
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 10
Human (de-) phosphorylation sites: 10; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 15
Human phosphorylation targets: 15; Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00278 Entrez Gene ID: 1460 OMIM ID: 115441 Swissprot Accession: P67870; B0UXA9;