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Description for Protein CSNK1D

casein kinase 1, delta
17 total interacting proteins; 8 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • S_T_kinase: Serine/Threonine protein kinases, catalytic domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.11.1
    KEGG - Orthology:
    K08959
    KEGG - Pathway(s):
    hsa04340; hsa04540; hsa04710
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    CKI delta; CKID; Casein kinase 1, delta isoform 2; Casein kinase 1 delta isoform 1
    Approved Symbol:
    CSNK1D
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 27
    Human (de-) phosphorylation sites: 27; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 18
    Human phosphorylation targets: 16; Predicted platelet targets: 2
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Familial advanced sleep-phase syndrome(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 02920 Entrez Gene ID: 1453 OMIM ID: 600864 Swissprot Accession: P48730;