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Description for Protein CSK

c-src tyrosine kinase
47 total interacting proteins; 30 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 7/0)
(membrane: 1; microparticles: 1; platelet: 6; secretome: 1)
Summary:
(PubMed Links)
Domains and Motifs:
  • SH3: Src homology 3 domains
  • Tyr_Kinase: tyrosine kinase domain
  • SH2: Src homology 2 domains
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.7.10.2
    KEGG - Orthology:
    K05728
    KEGG - Pathway(s):
    hsa04062; hsa04722; hsa04810; hsa05120; hsa05131
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Cytoplasmic tyrosine kinase; c Src kinase; Protein tyrosine kinase CYL; Tyrosine protein kinase CSK
    Approved Symbol:
    CSK
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 4
    Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 13
    Human phosphorylation targets: 13; Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Staurosporine(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00496 Entrez Gene ID: 1445 OMIM ID: 124095 Swissprot Accession: P41240; B2R6Q4; A8K3B6;