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Description for Protein CSF3

colony stimulating factor 3 (granulocyte)
2 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • IL6: Interleukin-6 homologues
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K05423
    KEGG - Pathway(s):
    hsa04060; hsa04630; hsa04640; hsa05144
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Granulocyte colony stimulating factor; GCSF; Pluripoietin; Filgrastim; Lenograstim; Colony stimulating factor 3 isoform b; Colony stimulating factor 3 isoform c; Colony stimulating factor 3 isoform a
    Approved Symbol:
    CSF3
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00736 Entrez Gene ID: 1440 OMIM ID: 138970 Swissprot Accession: P09919; Q6FH65; Q8N4W3;