Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein CSF2RA

colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
10 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • TM: Transmembrane domain
  • FN3: Fibronectin type 3 domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K05066
    KEGG - Pathway(s):
    hsa04060; hsa04630; hsa04640; hsa05200
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Colony stimulating factor 2 receptor alpha chain isoform c; Colony stimulating factor 2 receptor alpha chain isoform e; CDw116; Granulocyte-macrophage colony stimulating factor receptor, low affinity alpha subunit; GMCSFR; Colony stimulating factor 2 receptor alpha chain isoform b; Colony stimulating factor 2 receptor alpha chain isoform a; GMR; CD116; CSF2R; CSF2RX; CSF2RY; CSF2RAX; CSF2RAY; MGC3848; MGC4838; GM-CSF-R-alpha
    Approved Symbol:
    CSF2RA
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • Sargramostim(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 7 : 1
  • Isoform 6 : 0
  • Isoform 5 : 0
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 02381 Entrez Gene ID: 1438 OMIM ID: 425000 Swissprot Accession: P15509; A7J003; B4DW68;