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Description for Protein SREK1

splicing regulatory glutamine/lysine-rich protein 1
52 total interacting proteins; 25 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the activities of other SR proteins (Barnard et al., 2002 [PubMed 11991645]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • RRM: RNA recognition motif

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K13165
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Serine arginine rich splicing regulatory protein 86; Splicing regulatory protein 508; SRrp86; SRrp508; DKFZp564B176; Splicing factor, arginine/serine-rich 12 isoform a; Splicing factor, arginine/serine-rich 12 isoform b
    Approved Symbol:
    SREK1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 23
    Human (de-) phosphorylation sites: 23; No platelet phosphorylation sites

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 18043 Entrez Gene ID: 140890 OMIM ID: 609268 Swissprot Accession: Q8WXA9B3KRJ9