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Description for Protein CPT1B

carnitine palmitoyltransferase 1B (muscle)
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 1)
Summary:
The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    2.3.1.21
    KEGG - Orthology:
    K08765
    KEGG - Pathway(s):
    hsa00071; hsa03320; hsa04920
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Carnitine palmitoyltransferase 1B isoform a; Carnitine O-palmitoyltransferase I, mitochondrial muscle isoform; CPTI-M; M-CPT1; CPTI, muscle; Carnitine palmitoyltransferase 1A(muscle); EC 2.3.1.21; Carnitine palmitoyltransferase 1B isoform b
    Approved Symbol:
    CPT1B
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 3
    Human (de-) phosphorylation sites: 3; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 8 : 2
  • Isoform 7 : 2
  • Isoform 6 : 2
  • Isoform 5 : 2
  • Isoform 4 : 2
  • Isoform 3 : 2
  • Isoform 2 : 2
  • Isoform 1 : 2
    • Additional Identifiers:

    HPRD: 09065 Entrez Gene ID: 1375 OMIM ID: 601987 Swissprot Accession: B7Z4U4; Q92523; B7Z5T8;