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Description for Protein CPA1

carboxypeptidase A1 (pancreatic)
No Interacting Proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
Three different forms of human pancreatic procarboxypeptidase A have been isolated. This gene encodes a monomeric pancreatic exopeptidase involved in zymogen inhibition. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • Zn_pept: Alpha-L-fucosidase
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.4.17.1
    KEGG - Orthology:
    K08779
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Procarboxypeptidase A1 pancreatic; CPA
    Approved Symbol:
    CPA1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

  • (2R)-2-benzyl-3-nitropropanoic acid(db);
  • (2R)-4,4-dihydroxy-5-nitro-2-(phenylmethyl)pentanoic acid(db);
  • 2-Benzyl-3-Iodopropanoic Acid(db);
  • Alpha-Hydroxy-Beta-Phenyl-Propionic Acid(db);
  • D-Cysteine(db);
  • D-[(Amino)Carbonyl]Phenylalanine(db);
  • D-[(N-Hydroxyamino)Carbonyl]Phenylalanine(db);
  • L-BENZYLSUCCINIC ACID(db);
  • L-[(N-Hydroxyamino)Carbonyl]Phenylalanine(db);
  • O-(((1R)-((N-(PHENYL-METHOXY-CARBONYL)-ALANYL)-AMINO)METHYL)HYDROXYPHOSPHINYL)3-L-PHENYLLACTATE(db);
  • O-(((1R)-((N-PHENYLMETHOXYCARBONYL-L-ALANYL)AMINO)ETHYL)HYDROXYPHOSPHONO)-L-BENZYLACETIC ACID(db);
  • OCTANE-1,3,5,7-TETRACARBOXYLIC ACID(db);
  • Phenylalanine-N-Sulfonamide(db)

    Associated Genetic Diseases:

    None Available
    		• Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00269 Entrez Gene ID: 1357 OMIM ID: 114850 Swissprot Accession: P15085;