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Description for Protein KLF6

Kruppel-like factor 6
13 total interacting proteins; 1 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a member of the Kruppel-like family of transcription factors. The zinc finger protein is a transcriptional activator, and functions as a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene, some of which are implicated in carcinogenesis. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • ZNFC2: zinc finger
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K09207
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    COPEB; Proto oncogene BCD1; Transcription factor ZF9; ZF9; Kruppel like factor 6; GC rich sites binding factor GBF; CPBP; GBF; PAC1; ST12; DKFZp686N0199; Prostate adenocarcinoma-1; Suppression of tumorigenicity 12 (prostate); B cell derived 1; BCD1
    Approved Symbol:
    KLF6
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

  • Gastric cancer, somatic(Pd);
  • Prostate cancer, somatic(Pd)
    		• Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03632 Entrez Gene ID: 1316 OMIM ID: 602053 Swissprot Accession: Q99612;