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Description for Protein COL13A1

collagen, type XIII, alpha 1
7 total interacting proteins; 5 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes the alpha chain of one of the nonfibrillar collagens. The function of this gene product is not known, however, it has been detected at low levels in all connective tissue-producing cells so it may serve a general function in connective tissues. Unlike most of the collagens, which are secreted into the extracellular matrix, collagen XIII contains a transmembrane domain and the protein has been localized to the plasma membrane. The transcripts for this gene undergo complex and extensive splicing involving at least eight exons. Like other collagens, collagen XIII is a trimer; it is not known whether this trimer is composed of one or more than one alpha chain isomer. A number of alternatively spliced transcript variants have been described, but the full length nature of some of them has not been determined. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • COLL: Collagen triple helix repeat (20 copies)
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Alpha 1 type XIII collagen isoform 11; Alpha 1 type XIII collagen isoform 12; Alpha 1 type XIII collagen isoform 13; Alpha 1 type XIII collagen isoform 14; Alpha 1 type XIII collagen isoform 15; Alpha 1 type XIII collagen isoform 16; Alpha 1 type XIII collagen isoform 17; Alpha 1 type XIII collagen isoform 18; Alpha 1 type XIII collagen isoform 19; Alpha 1 type XIII collagen isoform 2; Alpha 1 type XIII collagen isoform 3; Alpha 1 type XIII collagen isoform 4; Alpha 1 type XIII collagen isoform 5; Alpha 1 type XIII collagen isoform 6; Alpha 1 type XIII collagen isoform 7; Alpha 1 type XIII collagen isoform 9; Alpha 1 type XIII collagen isoform 10; Alpha 1 type XIII collagen isoform 1
    Approved Symbol:
    COL13A1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
    00383_20(0)
    00383_19(0)
    00383_18(0)
    00383_17(0)
    00383_16(0)
    00383_15(0)
    00383_14(0)
    00383_13(0)
    00383_12(0)
    00383_11(0)
    00383_10(0)
  • Isoform 9 : 0
  • Isoform 8 : 0
  • Isoform 7 : 0
  • Isoform 6 : 0
  • Isoform 5 : 0
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 00383 Entrez Gene ID: 1305 OMIM ID: 120350 Swissprot Accession: Q5TAT6;