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Description for Protein PIGU

phosphatidylinositol glycan anchor biosynthesis, class U
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Cdc91, a predicted integral membrane protein that may function in cell division control. The protein encoded by this gene is the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • SP: Signal Peptide
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K05293
    KEGG - Pathway(s):
    hsa00563; hsa01100
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    PIGU; MGC40420; GPI transamidase component; Phosphatidylinositol glycan biosynthesis, class U protein; CDC91 cell division cycle 91like 1; GPI transamidase component PIGU; UNQ3055/PRO9875; CDC91L1; GAB1; phosphatidylinositol glycan anchor biosynthesis, class U; CDC91-like 1 protein
    Approved Symbol:
    PIGU
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 9
    • Additional Identifiers:

    HPRD: 12250 Entrez Gene ID: 128869 OMIM ID: 608528 Swissprot Accession: Q9H490;