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Description for Protein CCR7

chemokine (C-C motif) receptor 7
3 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K04182
    KEGG - Pathway(s):
    hsa04060; hsa04062
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Chemokine, CC motif, receptor 7; CC CKR7; MIP3 beta receptor; EBV induced G protein coupled receptor 1; EBI1; BLR2; CMKBR7; EVI1; Epstein barr virus induced gene 1; Lymphocyte specific G protein coupled peptide receptor
    Approved Symbol:
    CCR7
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 10
    Human (de-) phosphorylation sites: 10; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 7
    • Additional Identifiers:

    HPRD: 02588 Entrez Gene ID: 1236 OMIM ID: 600242 Swissprot Accession: P32248; A0N0Q0;