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Description for Protein SENP8

SUMO/sentrin specific peptidase family member 8
2 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants. (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
3.4.22.-
KEGG - Orthology:
K08597
KEGG - Pathway(s):
None Available
Nomenclature / Alternative Names:
SUMO/sentrin specific protease family member 8; Sentrin specific protease 8; Cysteine protease FKSG8; NEDP1; PRSC2; DEN1; Deneddylase 1; NEDD8 specific protease 1
Approved Symbol:
SENP8
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 2
Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09784 Entrez Gene ID: 123228 OMIM ID: 608659 Swissprot Accession: Q96LD8; A8K8D3;