Search

Search for a specific protein in the Platelet Interactome


(Example: vasp)

 

Advanced Search

Get detailed protein information focusing on various characteristics and extract interaction networks

 

Legend

 

About

Go Back

Description for Protein UBE2J2

ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast)
5 total interacting proteins; 2 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is located in the membrane of the endoplasmic reticulum. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • UBC: Ubiquitin-conjugating enzyme E2, catalytic domain homologues
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    6.3.2.19
    KEGG - Orthology:
    K04554
    KEGG - Pathway(s):
    hsa04120; hsa05012
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    Ubiquitin conjugating enzyme E2, J2 isoform 2; Ubiquitin conjugating enzyme E2, J2 isoform 1; Ubiquitin conjugating enzyme E2, J2 isoform 3; UBC6 homolog; EC 6.3.2.19; Non canonical ubiquitin conjugating enzyme 2; NCUBE2; Ubc6p; PRO2121; Ubiquitin conjugating enzyme 6
    Approved Symbol:
    UBE2J2
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 0
    No human (de-) phosphorylation sites; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 5 : 1
  • Isoform 4 : 1
  • Isoform 3 : 0
  • Isoform 2 : 1
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 15600 Entrez Gene ID: 118424 OMIM ID: - Swissprot Accession: Q8N2K1; A8MYC7; A6NGS0;