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Description for Protein AP2S1

adaptor-related protein complex 2, sigma 1 subunit
7 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/1)
(platelet: 1)
Summary:
One of two major clathrin-associated adaptor complexes, AP-2, is a heterotetramer which is associated with the plasma membrane. This complex is composed of two large chains, a medium chain, and a small chain. This gene encodes the small chain of this complex. Alternative splicing has been observed in this gene and results in two known transcripts. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K11827
KEGG - Pathway(s):
hsa04144; hsa05016
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
Adaptor-related protein complex 2, sigma 1 subunit isoform AP17; Adaptor related protein complex 2, sigma 1 subunit; CLAPS2; Clathrin adaptor protein AP17; AP17; AP17 delta; Plasma membrane adaptor Ap2, 17 KD protein; Ha2, 17KD subunit; Adaptor-related protein complex 2, sigma 1 subunit isoform AP17delta
Approved Symbol:
AP2S1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 2
Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 03762 Entrez Gene ID: 1175 OMIM ID: 602242 Swissprot Accession: P53680;