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Description for Protein AP1S1

adaptor-related protein complex 1, sigma 1 subunit
10 total interacting proteins; 7 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 2/0)
(platelet: 4)
Summary:
The protein encoded by this gene is part of the clathrin coat assembly complex which links clathrin to receptors in coated vesicles. These vesicles are involved in endocytosis and Golgi processing. This protein, as well as beta-prime-adaptin, gamma-adaptin, and the medium (mu) chain AP47, form the AP-1 assembly protein complex located at the Golgi vesicle. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K12394
KEGG - Pathway(s):
hsa04142
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
AP19; CLAPS1; SIGMA1A; AP1S1adaptor-related protein complex 1, sigma 1 subunit; H_DJ0747G18.2; WUGSC:H_DJ0747G18.2; clathrin coat assembly protein AP19; clathrin-associated/assembly/adaptor protein, small 1 (19kD); Adaptor-related protein complex 1, sigma 1 subunit isoform 1; Adaptor-related protein complex 1, sigma 1 subunit isoform 2
Approved Symbol:
AP1S1
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 1
Human (de-) phosphorylation sites: 1; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 04635 Entrez Gene ID: 1174 OMIM ID: 603531 Swissprot Accession: P61966;