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Description for Protein DNTTIP1

deoxynucleotidyltransferase, terminal, interacting protein 1
2 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
DNTTIP1 binds DNA and enhances the activity of terminal deoxynucleotidyltransferase (TDT, or DNTT; MIM 187410), a DNA polymerase that catalyzes the polymerization of DNA in the absence of a DNA template (Yamashita et al., 2001 [PubMed 11473582]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
  • NLS: Nuclear localization signal
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    K08707
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    TdT binding protein; Chromosome 20 open reading frame 167; Novel protein similar to synaptotagmin 1 SYT, P65 isoform 1; Tdif1; C20orf167; dJ447F3.4; TdT interacting factor 1; TdIF1
    Approved Symbol:
    DNTTIP1
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 2
    Human (de-) phosphorylation sites: 2; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 16831 Entrez Gene ID: 116092 OMIM ID: 611388 Swissprot Accession: Q9H147;