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Description for Protein OSBPL8

oxysterol binding protein-like 8
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 1/0)
(platelet: 5)
Summary:
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • PH: Pleckstrin homology domain.
  • CC: Coiled Coil
  • TM: Transmembrane domain
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    OSBP10; OSBP related protein 8; Oxysterol binding protein like protein 8; Oxysterol binding protein related protein 8; Oxysterol binding protein like protein 8 isoform a; Oxysterol binding protein like protein 8 isoform b; KIAA1451; ORP8
    Approved Symbol:
    OSBPL8
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 51
    Human (de-) phosphorylation sites: 51; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 2 : 1
  • Isoform 1 : 1
    • Additional Identifiers:

    HPRD: 09478 Entrez Gene ID: 114882 OMIM ID: 606736 Swissprot Accession: Q5HYM3; Q9BZF1;