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Description for Protein MGLL

monoglyceride lipase
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 8/1)
(membrane: 1; microparticles: 1; platelet: 16; secretome: 2)
Summary:
Monoglyceride lipase (MGLL; EC 3.1.1.23) functions together with hormone-sensitive lipase (LIPE; MIM 151750) to hydrolyze intracellular triglyceride stores in adipocytes and other cells to fatty acids and glycerol. MGLL may also complement lipoprotein lipase (LPL; MIM 238600) in completing hydrolysis of monoglycerides resulting from degradation of lipoprotein triglycerides (Karlsson et al., 2001 [PubMed 11470505]).[supplied by OMIM] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
3.1.1.23
KEGG - Orthology:
K01054
KEGG - Pathway(s):
hsa00561; hsa01100
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
MGL; HU-K5; Lysophospholipase like; EC 3.1.1.23; Lysophospholipase homolog; Monoglyceride lipase isoform 1; Monoglyceride lipase isoform 2
Approved Symbol:
MGLL
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 17574 Entrez Gene ID: 11343 OMIM ID: 609699 Swissprot Accession: B3KRC2; Q99685; Q6IBG9;