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Description for Protein EXOSC8

exosome component 8
23 total interacting proteins; 6 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 0/0)
(Not detected in platelets)
Summary:
This gene encodes a 3'-5' exoribonuclease that specifically interacts with mRNAs containing AU-rich elements. The encoded protein is part of the exosome complex that is important for the degradation of numerous RNA species. A pseudogene of this gene is found on chromosome 6. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
None Available
Gene Ontology:
Gene Ontology Annotations
KEGG - Enzyme ID(s):
None Available
KEGG - Orthology:
K12586
KEGG - Pathway(s):
hsa03018
(The yellow boxes represents platelet proteins)
Nomenclature / Alternative Names:
OIP2; CIP3; p9; EAP2; RRP43; Rrp43p; Exosome component 8; Ribosomal RNA processing protein 43; Exosome complex exonuclease RRP43
Approved Symbol:
EXOSC8
(De-) Phosphorylations:
Total (de-) phosphorylation sites: 0
No human (de-) phosphorylation sites; No platelet phosphorylation sites
Phosphorylation Targets:
Total phosphorylation targets: 0
Human phosphorylation targets: 0;Predicted platelet targets: 0
Protein Characteristics:
Isoform-specific Information
Icon DrugsAssociated Drugs (DrugBank Accession):

None Available

Associated Genetic Diseases:

None Available
Predicted Transmembrane Domains:
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 09351 Entrez Gene ID: 11340 OMIM ID: 606019 Swissprot Accession: Q96B26;