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Description for Protein ACOT7

acyl-CoA thioesterase 7
1 total interacting proteins;
Icon Book Platelet Evidence (proteome studies/others : 2/0)
(platelet: 6; secretome: 5)
Summary:
This gene encodes a member of the acyl coenzyme family. The encoded protein hydrolyzes the CoA thioester of palmitoyl-CoA and other long-chain fatty acids. Decreased expression of this gene may be associated with mesial temporal lobe epilepsy. Alternatively spliced transcript variants encoding distinct isoforms with different subcellular locations have been characterized. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • NLS: Nuclear localization signal
    • Gene Ontology:
    Gene Ontology Annotations
    KEGG - Enzyme ID(s):
    3.1.2.2
    KEGG - Orthology:
    K01068
    KEGG - Pathway(s):
    hsa01040
    (The yellow boxes represents platelet proteins)
    Nomenclature / Alternative Names:
    BACH; RP1-120G22.10; hBACH; Acyl-CoA thioesterase 2; Acyl-CoA thioesterase long chain; Brain acyl-CoA hydrolase; Acyl-CoA thioesterase 7 isoform hBACHa; Acyl-CoA thioesterase 7 isoform hBACHc; Acyl-CoA thioesterase 7 isoform hBACHd; EC 3.1.2.2; CTE-IIa; Acyl-CoA thioesterase 7 isoform hBACHb; ACT; ACH1; LACH1; CTE-II; MGC1126; Long chain acyl-CoA thioester hydrolase
    Approved Symbol:
    ACOT7
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 4
    Human (de-) phosphorylation sites: 4; No platelet phosphorylation sites
    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    		Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available

    Associated Genetic Diseases:

    None Available
    		Predicted Transmembrane Domains:
  • Isoform 6 : 0
  • Isoform 5 : 0
  • Isoform 4 : 0
  • Isoform 3 : 0
  • Isoform 2 : 0
  • Isoform 1 : 0
    • Additional Identifiers:

    HPRD: 12517 Entrez Gene ID: 11332 OMIM ID: 602587 Swissprot Accession: O00154;