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Description for Protein SYNRG

synergin, gamma
7 total interacting proteins; 4 platelet interacting proteins
Icon Book Platelet Evidence (proteome studies/others : 1/2)
(phosphoproteome: 1; platelet: 1; undefined: 1)
Summary:
This gene encodes a protein that interacts with the gamma subunit of AP1 clathrin-adaptor complex. The AP1 complex is located at the trans-Golgi network and associates specific proteins with clathrin-coated vesicles. This encoded protein may act to connect the AP1 complex to other proteins. Alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq] (PubMed Links)
Domains and Motifs:
  • CC: Coiled Coil
  • EH: Eps15 homology domain

  • Gene Ontology:
    Gene Ontology Annotations

    KEGG - Enzyme ID(s):
    None Available
    KEGG - Orthology:
    None Available
    KEGG - Pathway(s):
    None Available
    Nomenclature / Alternative Names:
    Adaptor related protien complex 1 gamma subunit binding protien 1; SYNG; AP1 gamma subunit binding protein 1 isoform 1; AP1 gamma subunit binding protein 1 isoform 2; MGC104959; AP1 gamma subunit binding protein 1
    Approved Symbol:
    SYNRG
    (De-) Phosphorylations:
    Total (de-) phosphorylation sites: 53
    Human (de-) phosphorylation sites: 52; Platelet phosphorylation sites: 1

    Phosphorylation Targets:
    Total phosphorylation targets: 0
    Human phosphorylation targets: 0;Predicted platelet targets: 0
    Protein Characteristics:
    Isoform-specific Information
    Icon DrugsAssociated Drugs (DrugBank Accession):

    None Available


    Associated Genetic Diseases:

    None Available
    Predicted Transmembrane Domains:
  • Isoform 2 : 0
  • Isoform 1 : 0
  • Additional Identifiers:

    HPRD: 06291 Entrez Gene ID: 11276 OMIM ID: 607291 Swissprot Accession: Q9UMZ2B7ZKZ2